Dataset used in research paper entitled "Plasma Circular-RNA 0005567 as a Potential Marker of Disease Activity in Rheumatoid Arthritis"
Date
2023-12-28
Authors
Journal Title
Journal ISSN
Volume Title
Depositor
Publisher
MDPI
Abstract
Circular RNAs (circRNAs) are noncoding molecules and are generated through back splicing. The 3′ and 5′ ends of the RNAs are covalently linked and form a loop structure, making it resistant to RNA exonucleases. Thus, circRNAs are biologically stable and may be considered as potential molecular markers of various diseases in tissues and biofluids. CircRNAs may regulate gene expression levels by acting as a microRNA sponge or by interacting with RNA binding proteins. The aim of the study was to find an association between plasma concentration of selected circRNAs and disease activity in patients with RA.
Description
A data set used to calculate the concentration level of the tested molecules in plasma samples, as well as to quantify transcripts expression after transfection of cell lines.
Keywords
circular RNA, Rheumatoid Arthritis, non-coding RNA, epigenetics
Related publications
Plasma Circular-RNA 0005567 as a Potential Marker of Disease Activity in Rheumatoid Arthritis. Int. J. Mol. Sci. 2024, 25(1), 417; https://doi.org/10.3390/ijms25010417.
The license associated with this item
CC0 1.0 Universal
Research funding institutions
The study was carried out with funds from the MINIATURA 5 (project ID: 2021/05/X/NZ2/01697) of the National Science Centre, Poland.
Type
raw dataset