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Item type: Item , The impact of the intake level of immunomodulatory compo-nents from food and lifestyle factors on the type of symptoms, complications, and frequency of hospitalizations in patients with COVID-19(MDPI, 2026) Polak-Szczybyło, EwelinaThe COVID-19 pandemic has introduced new health challenges, and research on the impact of diet and lifestyle on the course of the disease has become crucial. The aim of this article is to analyze how the intake level of immunomodulatory components from food affects symptoms, complications, and hospitalizations in patients infected with SARS-CoV-2. An online survey was conducted among 741 individuals who had con-tracted COVID-19. Respondents were asked about the frequency of consumption of foods that are the primary sources of selected immunomodulatory components (ome-ga-3, vitamins A, E, D, C, iron, selenium, zinc, beta-carotene, probiotics) prior to ill-ness, as well as lifestyle factors such as physical activity, smoking, sleep duration, and stress levels. Additionally, participants were asked about symptoms during illness, complications afterward, and hospitalization due to the virus. It was shown that com-ponents such as omega-3 fatty acids, beta-carotene, vitamins A, E, D, and C, as well as iron, may have potential immunomodulatory effects in COVID-19 infections and re-duce the occurrence of symptoms, complications, and hospitalization risk. Paradoxi-cally, smoking was found to decrease the occurrence of some symptoms and complica-tions, while stress, lack of sleep, and low physical activity increased the severity of the disease. A well-balanced diet can significantly affect symptoms, complications, and the likelihood of hospitalization due to SARS-CoV-2 infection. It has been demonstrated that different foods and their components can influence the immune system and the occurrence of specific symptoms or complications.Item type: Item , RNA-Seq data - "Thiolutin Extends Replicative Lifespan by Rewiring Yeast Transcription and Metabolism"(Springer Nature, 2025-10-16) Mołoń, MateuszTranscription is a fundamental process that underlies gene expression and protein synthesis, with RNA polymerases serving as central regulators of cellular activity. Inhibition of RNA polymerases I, II, and III provides valuable insights into the coordination of gene expression, energy metabolism, and genome maintenance, and holds considerable therapeutic potential. Thiolutin, a well-established transcriptional inhibitor in yeast, remains an essential tool for probing the dynamics of RNA synthesis and global transcriptional control. Beyond its canonical role, thiolutin reduces intracellular ATP levels underscoring its multifaceted impact on metabolism. Here, we report for the first time that thiolutin markedly enhances the reproductive capacity of mitotically active yeast cells, thereby extending their replicative lifespan. In contrast, thiolutin accelerates chronological aging, revealing a striking divergence between replicative and chronological longevity. Moreover, thiolutin-mediated inhibition of RNA polymerases alters the expression of more than 60% of annotated genes, as demonstrated by RNA-Seq analysis, and profoundly reshapes the biochemical fingerprint of the cell as detected by Raman spectroscopy.Item type: Item , Comparison of the 36-item WHODAS 2.0 assessment by face-to-face or telephone interviews: a randomised, crossover study(2025) Sozańska, Agnieszka; Sozański, Bernard; Wilmowska-Pietruszyńska, Anna; Dzięcioł-Anikiej, Zofia; Hagner-Derengowska, Magdalena; Wiśniowska-Szurlej, AgnieszkaBackground/Objectives: We compared face-to-face and telephone administration of the 36-item WHODAS 2.0 in community-dwelling adults aged ≥60 years. Methods: In a randomized crossover study, 239 participants from south-eastern Poland were assigned to two groups differing in interview order. The interval between assessments averaged 14.3 ± 1.3 days. Agreement was evaluated using Cohen’s kappa, ICC and Bland–Altman analysis. Results: A total of 203 participants completed both surveys. Item-level agreement ranged from 85.71% to 98.03% (κ = 0.788–0.947). The total WHODAS score showed excellent agreement (ICC = 0.986). All domains demonstrated high agreement (ICC = 0.953–0.967). Bland–Altman analysis confirmed high consistency, with only 5.42% of results outside the 95% limits. Conclusions: Telephone administration of the 36-item WHODAS 2.0 provides results equivalent to face-to-face interviews in older adults and can be reliably used in clinical practice and screening when access to in-person assessment is limitedItem type: Item , The impact of stress intensity and ways of coping with it on the risk of eating disorders among polish students during the exam session(MDPI, 2025) Polak-Szczybyło, EwelinaPurpose: Eating disorders can affect all age groups, but most often they affect young people. Stressful situations such as an exam session very often exacerbate this prob-lem. Appropriate coping strategies can be a solution for people struggling with eating disorders. Methods: 500 polish students of various faculties were surveyed using the EAT-26 (Eating Attitudes Test-26) questionnaire, Mini-COPE (Coping Orientation to Problems Experienced inventory) and PSS 10 (The Perceived Stress Scale 10). The study was conducted during the examination session to recreate the stress conditions. Re-sults: The analysis showed that higher levels of stress were significantly associated with an increased risk of eating disorders, particularly in the dieting domain, with p=0.004. Coping strategies played a significant role, with substance use positively cor-related with increased risk (p<0.000001), while seeking instrumental and emotional support was negatively associated (p=0.0001). Conclusion: Stress levels were positively correlated with the likelihood of developing an eating disorder. Eating disorders are strongly linked to stress coping strategies. It should be considered whether teaching students relaxation techniques and methods of coping with stress could significantly reduce the incidence of eating disorders. The above-mentioned factors are related to gender, age, place of residence, year of study and field of study.Item type: Item , Zbieractwo krasnoborowika ceglastoporego (Neoboletus erythropus) w Polsce(2025-08-07) Łuczaj, ŁukaszAnkieta użytkowaniu krasnoborowika ceglastoporego w Polsce.