Repozytorium
Danych Badawczych
Uniwersytetu Rzeszowskiego

 

Recent Submissions

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Change in patients’ psychophysical performance following lumbar discectomy relative to the postoperative rehabilitation programme
(2019) Wolan-Nieroda, Andżelina; Sobański, Grzegorz; Guzik, Agnieszka; Maciejczak, Andrzej
Abstract Background. The aim of this study was to assess the change in psychophysical performance of patients after lumbar discectomy in relation to the postoperative rehabilitation programme. Material and Methods. The study involved 60 participants randomly divided into two groups of 30 individuals. Both groups participated in a basic version of the rehabilitation programme, and individuals in the study group additionally received manual therapy. The evaluation was performed twice, before the start and after the completion of the 3-month rehabilitation programme. The tests were carried out to measure static balance, functional status using Oswestry Disability Index (ODI) and Roland-Morris Disability Questionnaire (RMDQ), lumbar spine range of motion using the original Schober’s test and the intensity of pain using the Visual Analogue Scale (VAS). Results. Both groups showed significant improvement in most of the psychophysical parameters assessed (study versus control p<0.01;p<0.05), except for the parameters of balance. In the study group, significant changes occurred in all parameters except X average, Area circular and average velocity in trials with eyes closed and left leg stance after rehabilitation (p<0.05). The findings showed significant differences in the reduced pain intensity on the VAS (p=0.0001), improved functional status in ODI and improved static balance (p<0.01), in favour of the study group. Conclusion. The protocol which additionally included manual therapy was found to be more effective than the basic programme. Its superiority was reflected by greater pain reduction, more visibly improved functional status as well as improved static balance.
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Change in patients’ psychophysical performance following lumbar discectomy relative to the postoperative rehabilitation programme
(2019) Wolan-Nieroda, Andżelina; Sobański, Grzegorz; Guzik, Agnieszka; Maciejczak, Andrzej
Abstract Background. The aim of this study was to assess the change in psychophysical performance of patients after lumbar discectomy in relation to the postoperative rehabilitation programme. Material and Methods. The study involved 60 participants randomly divided into two groups of 30 individuals. Both groups participated in a basic version of the rehabilitation programme, and individuals in the study group additionally received manual therapy. The evaluation was performed twice, before the start and after the completion of the 3-month rehabilitation programme. The tests were carried out to measure static balance, functional status using Oswestry Disability Index (ODI) and Roland-Morris Disability Questionnaire (RMDQ), lumbar spine range of motion using the original Schober’s test and the intensity of pain using the Visual Analogue Scale (VAS). Results. Both groups showed significant improvement in most of the psychophysical parameters assessed (study versus control p<0.01;p<0.05), except for the parameters of balance. In the study group, significant changes occurred in all parameters except X average, Area circular and average velocity in trials with eyes closed and left leg stance after rehabilitation (p<0.05). The findings showed significant differences in the reduced pain intensity on the VAS (p=0.0001), improved functional status in ODI and improved static balance (p<0.01), in favour of the study group. Conclusion. The protocol which additionally included manual therapy was found to be more effective than the basic programme. Its superiority was reflected by greater pain reduction, more visibly improved functional status as well as improved static balance.
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Change in patients’ psychophysical performance following lumbar discectomy relative to the postoperative rehabilitation programme
(2023) Wolan-Nieroda, Andżelina; Sobański, Grzegorz; Guzik, Agnieszka; Maciejczak, Andrzej
Abstract Background: The aim of this study was to assess the change in psychophysical performance of patients after lumbar discectomy in relation to the postoperative rehabilitation programme. Material and Methods: The study involved 60 participants randomly divided into two groups of 30 individuals. Both groups participated in a basic version of the rehabilitation programme, and individuals in the study group additionally received manual therapy. The evaluation was performed twice, before the start and after the completion of the 3-month rehabilitation programme. The tests were carried out to measure static balance, functional status using Oswestry Disability Index (ODI) and Roland-Morris Disability Questionnaire (RMDQ), lumbar spine range of motion using the original Schober’s test and the intensity of pain using the Visual Analogue Scale (VAS). Results: Both groups showed significant improvement in most of the psychophysical parameters assessed (study versus control p<0.01;p<0.05), except for the parameters of balance. In the study group, significant changes occurred in all parameters except X average, Area circular and average velocity in trials with eyes closed and left leg stance after rehabilitation (p<0.05). The findings showed significant differences in the reduced pain intensity on the VAS (p=0.0001), improved functional status in ODI and improved static balance (p<0.01), in favour of the study group. Conclusion: The protocol which additionally included manual therapy was found to be more effective than the basic programme. Its superiority was reflected by greater pain reduction, more visibly improved functional status as well as improved static balance.
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The Antibacterial Properties of Polish Honey against Streptococcus mutans—A Causative Agent of Dental Caries
(MDPI, 2024) Grabek-Lejko, Dorota; Hyrchel, Tomasz
Streptococcus mutans is considered the main pathogen responsible for dental caries, one of the major infectious diseases, affecting more than 4 billion people worldwide. Honey is a natural product with well-known antibacterial potential against several human pathogens. The aim of the study was to evaluate the antibacterial efficacy of Polish honey against S. mutans and analyze the role of some bioactive substances on its antibacterial action. The antibacterial potential of different honey varieties (goldenrod, buckwheat, honeydew, and lime) was analyzed using a microdilution assay. Manuka and artificial honey were used as controls. The content of GOX, hydrogen peroxide, total polyphenols, and antioxidant potential was assayed in honey. The influence of catalase and proteinase K on antibacterial activity as well as antibiofilm action was also determined. The strongest antibacterial activity was observed for buckwheat, honeydew, and manuka honey, which were also characterized by the highest antioxidant activity and polyphenols content. Catalase treatment decreases the antibacterial activity of honey, while proteinase K treatment influences the antibacterial potential of honey slightly less. Obtained results suggest that honey can be a good natural product against S. mutans, and hydrogen peroxide was identified as a crucial contributor to its antimicrobial action.
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Engineering of Ogataea polymorpha strains with ability for high-temperature alcoholic fermentation of cellobiose
(Oxford University Press, 2024-02-22) Vasylyshyn, Roksolana; Dmytruk, Olena; Sibirny, Andriy; Ruchala, Justyna
Successful conversion of cellulosic biomass into biofuels requires organisms capable of efficiently utilizing xylose as well as cellodextrins and glucose. Ogataea (Hansenula) polymorpha is the natural xylose-metabolizing organism and is one of the most thermotolerant yeasts known, with a maximum growth temperature above 50°C. Cellobiose-fermenting strains, derivatives of an improved ethanol producer from xylose O. polymorpha BEP/cat8∆, were constructed in this work by the introduction of heterologous genes encoding cellodextrin transporters (CDTs) and intracellular enzymes (β-glucosidase or cellobiose phosphorylase) that hydrolyze cellobiose. For this purpose, the genes gh1-1 of β-glucosidase, CDT-1m and CDT-2m of cellodextrin transporters from Neurospora crassa and the CBP gene coding for cellobiose phosphorylase from Saccharophagus degradans, were successfully expressed in O. polymorpha. Through metabolic engineering and mutagenesis, strains BEP/cat8∆/gh1-1/CDT-1m and BEP/cat8∆/CBP-1/CDT-2mAM were developed, showing improved parameters for high-temperature alcoholic fermentation of cellobiose. The study highlights the need for further optimization to enhance ethanol yields and elucidate cellobiose metabolism intricacies in O. polymorpha yeast. This is the first report of the successful development of stable methylotrophic thermotolerant strains of O. polymorpha capable of coutilizing cellobiose, glucose, and xylose under high-temperature alcoholic fermentation conditions at 45°C.