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Item type: Item , The impact of stress intensity and ways of coping with it on the risk of eating disorders among polish students during the exam session(MDPI, 2025) Polak-Szczybyło, EwelinaPurpose: Eating disorders can affect all age groups, but most often they affect young people. Stressful situations such as an exam session very often exacerbate this prob-lem. Appropriate coping strategies can be a solution for people struggling with eating disorders. Methods: 500 polish students of various faculties were surveyed using the EAT-26 (Eating Attitudes Test-26) questionnaire, Mini-COPE (Coping Orientation to Problems Experienced inventory) and PSS 10 (The Perceived Stress Scale 10). The study was conducted during the examination session to recreate the stress conditions. Re-sults: The analysis showed that higher levels of stress were significantly associated with an increased risk of eating disorders, particularly in the dieting domain, with p=0.004. Coping strategies played a significant role, with substance use positively cor-related with increased risk (p<0.000001), while seeking instrumental and emotional support was negatively associated (p=0.0001). Conclusion: Stress levels were positively correlated with the likelihood of developing an eating disorder. Eating disorders are strongly linked to stress coping strategies. It should be considered whether teaching students relaxation techniques and methods of coping with stress could significantly reduce the incidence of eating disorders. The above-mentioned factors are related to gender, age, place of residence, year of study and field of study.Item type: Item , Zbieractwo krasnoborowika ceglastoporego (Neoboletus erythropus) w Polsce(2025-08-07) Łuczaj, ŁukaszAnkieta użytkowaniu krasnoborowika ceglastoporego w Polsce.Item type: Item , Dataset used in research paper entitled “ITGA1, the alpha 1 subunit of integrin receptor, is a novel marker of drug-resistant senescent melanoma cells in vitro”(Springer Nature, 2025-04-09) Słaby, Julia; Wnuk, Maciej; Błoniarz, Dominika; Stec, Paulina; Szmatoła, Tomasz; Kaznowska, Ewa; Reich, Adam; Moros, María; Lewińska, AnnaChemotherapy-induced senescence may promote drug resistance and treatment failure. Precise detection and elimination of senescent cancer cells is considered as a novel promising anticancer strategy. However, data on senescence-associated skin cancer cell surface markers as potential therapeutic targets are limited. In the present study, we have established two models of drug-induced senescence in vitro using DNA damaging chemotherapeutics, namely etoposide (0.75-5 µM) and cisplatin (1.25-5 µM), and ten skin cancer cell lines, both melanoma (n = 8, A375, G-361, MM370, SH-4, SK-MEL-1, MeWo, MM127, RPMI-7951) and non-melanoma (n = 2, A431, MCC13), to investigate the levels of 97 cell surface markers. Initial gene expression analysis revealed the increasing tendency in the levels of seven transcripts (ITGA1, ITGA3, VAMP3, STX4, ARMCX3, ULBP2, and PLAUR) and five transcripts (ITGA1, ITGA3, STX4, ARMCX3, and PLAUR) in five etoposide and cisplatin-induced senescent melanoma cell lines, respectively, compared to corresponding proliferating cells. Elevated pools of integrin α1 (ITGA1) were confirmed at mRNA and protein levels in eight drug-induced senescent melanoma cell lines. Similar pattern of changes in integrin α1 levels was not observed in drug-induced senescent non-melanoma skin cancer cells. Analysis using clinical melanoma samples also showed that the levels of ITGA1 and ITGA3 were correlated with the presence of melanoma cells in a section. We document that integrin α1 can be considered as a novel marker of drug-induced senescent melanoma cells. Thus, we postulate that new integrin α1-based targeted therapies can be designed and tested against drug-induced senescent melanoma cells.Item type: Item , Comparison of Invasive and Non-Invasive Blood Pressure Measurements During Mechanical Thrombectomy for Acute Ischemic Stroke Under General Anesthesia – A Pilot Study.(2025-07-15) Wiącek, MarcinIntroduction Intra-procedural hypotension during endovascular therapy (EVT) for acute ischemic stroke (AIS) is linked to poorer outcomes. Although continuous invasive blood pressure (IBP) monitoring could help guide timely clinical decisions, it is not routinely implemented during mechanical thrombectomy (MT) under general anesthesia. Objectives This study aimed to assess the agreement between continuous IBP and intermittent non-invasive blood pressure (NIBP) monitoring during EVT and to evaluate whether IBP monitoring impacts procedural timing. Patients and Methods In this prospective observational study, 30 patients undergoing MT for AIS under general anesthesia were enrolled. Blood pressure was simultaneously recorded using radial arterial lines (IBP) and oscillometric cuffs (NIBP, every 5 minutes). Bland–Altman plots were used to assess agreement. Clinically relevant discrepancies and door-to-groin (DTG) times were compared between patients with planned IBP and those without. Results A total of 481 matched BP readings were analyzed. Mean differences between IBP and NIBP for systolic blood pressure (SBP) and mean arterial pressure (MAP) were small (–0.64 mmHg and –0.99 mmHg, respectively), but agreement limits were wide (SBP: –40.6 to 39.4 mmHg; MAP: –28.5 to 26.5 mmHg). Diastolic pressure showed poor agreement (mean bias –7.64 mmHg). Significant SBP differences (≥20 mmHg) occurred in 41.0% of procedure time, and MAP discrepancies (>15 mmHg) in 29.6%. Median DTG times were similar between groups (41 vs. 38 minutes; p = 0.217). Conclusions Intermittent NIBP monitoring demonstrates limited agreement with continuous IBP, particularly under hypotensive conditions, and may fail to detect meaningful hemodynamic shifts. Importantly, the use of IBP does not appear to delay treatment initiation. These results support further investigation in larger studies.Item type: Item , Frequency, preferences, and determinants of energy drink consumption among young polish people after the introduction of the ban on sales to minors(MDPI, 2025) Polak-Szczybyło, EwelinaBackground: In Poland, consumption of energy drink among young people has changed significantly following the introduction of a ban on sales to minors. This reg-ulatory measure was intended to address growing concerns about the health effects of high caffeine consumption among teenagers. The aim of the article was to assess the effectiveness of the ban on the sale of energy drinks to minors and to examine the level of knowledge of young people about the harmfulness of consuming these drinks. Methods: The study was conducted in 2024 in Poland after the introduction of a law that prohibited the consumption of energy drinks among minors. The study group consisted of 999 people aged 15-17. Results: 52% of the respondents declared that they consume ED, and 68% reduced their consumption after the introduction of regulations prohibiting sales to minors. This type of drink is used more frequently by men, and age and frequency were also positively correlated. The factors that most often influenced the choice of ED are price, taste, package size, caffeine content, composition, or recommendations from friends. Conclusions: Although a large percentage of minors still drink energy drinks, new regulations have had an impact on limiting the amount of ED consumed.