Polak-Szczybyło, EwelinaPolak-Szczybyło, EwelinaTabarkiewicz, Jacek2024-11-192024-11-192024https://rdb.ur.edu.pl/handle/item/54Serum resistin and adiponectin levels in obese adults were compared with the results of a body composition analysis, a three-day food diary, a questionnaire and a standardized food frequency questionnaire FFQ-6. Additionally, the Adiponectin/Resistin index was calculated and related to the other results.Background: Low-grade inflammation resulting from processes occurring in the adipose tissue of obese people is a factor in the occurrence of numerous diseases. Current research focuses on ways to regulate immunological mechanisms in adipose tissue in order to minimize the consequences for the health. Methods: Body composition analysis using BIA was performed among 84 adults with obesity (BMI ≥ 30 kg/m2). Serum was collected to analyze the concentration of adiponectin (ApN) and resistin. The subjects additionally completed a food frequency questionnaire FFQ-6 and a three-days food diary. Adiponectin-resistin index (AR index) was calculated. Results: Re-sistin showed a positive correlation with BMI and subcutaneous adipose tissue content. AR index value was also positively associated with the amount of adipose tissue and body mass. Adi-ponectin level in the blood of the studied individuals decreased with the content of lean tissue. Adiponectin level also decreased with the amount of carbohydrates, e.g. starch, and glycemic load of the diet. Resistin decreased in patients who frequently consumed white pasta and red meat, while AR index was positively associated with the amount of white rice and SFA and MUFA fatty acids consumed and negatively with the frequent consumption of carbohydrates, including starch. Physical activity was negatively correlated with adiponectin levels and AR index. Con-clusion: Body composition significantly affected the AR index and concentration of resistin and adiponectin in the blood of the subjects. Dietary factors also had a significant effect.enCC0 1.0 Universallow-grade inflammationadiponectinresistinobesityA/R indexraw dataset